ProposalCentral link https://proposalcentral.com/grantopportunities.asp?GMID=137#

Research proposals should focus on innovative clinical research to advance development of treatments to stop or slow ankle osteoarthritis (including hindfoot).  A goal of this funding mechanism is to support research that will build data that will be used to gain funding from large institutional sources (such as the NIH, DoD, PCORI, VA and others).  Clinical studies should utilize patient reported outcomes, with use of imaging and clinical samples being highly encouraged.  Studies should comply with clinical and institutional review board (IRB) requirements.  Animal studies are not allowed.

Proposed research may include, but not limited to:

• Optimization of biomechanics for ankle OA
• Slow/stop adjacent joint arthritis in ankle or hindfoot, including subtalar joint
• Development of tests or assays using clinical specimens to detect the early stages of ankle OA
• Development of therapeutics, including “orthobiologics”, that could modify the course of ankle OA
• Genetic susceptibility to ankle OA
• Database studies