CDMRP Tuberous Sclerosis Complex (TSC) Research Program

Sponsor Deadline: 

Jul 7, 2023

Letter of Intent Deadline: 

Jun 8, 2023


Department of Defense/CDMRP

UI Contact: 

View the announcements for three upcoming programs

Applications submitted to the FY23 TSCRP must address one or more of the following Focus Areas:

  • Understanding, preventing, and treating the features of TSC-Associated Neuropsychiatric Disorders (TAND) and reducing their impact, including pharmacological, behavioral, and surgical interventions
  • Strategies for eradicating tumors associated with TSC and TSC-associated lymphangioleiomyomatosis (LAM), including gaining a deeper mechanistic understanding of tumor microenvironment, TSC signaling and mTOR-independent pathways
  • Preventing, epilepsy, improving treatment, and mitigating neurodevelopmental and adverse outcomes associated with TSC-related seizures
  • Developing, assessing, and testing emerging technologies including imaging and molecular therapeutic strategies, such as gene therapy, to improve outcomes in TSC