ProposalCentral link https://proposalcentral.com/grantopportunities.asp?GMID=194#

COG Hematopoietic Malignancies Integrated Translational Science Center – 2023 Request for Applications: Translational Pilot Studies for Hematopoietic Malignancies

Dedicated funds are available for pilot studies to support translational studies as part of the Hematopoietic Malignancies Integrated Translational Sciences Center (HM-ITSC). The purpose of the HM-ITSC is to foster the development and implementation of translational research studies that will support future clinical trials in hematopoietic malignancies. The Hematologic Malignancies Translational Pilot Studies Program (HM-TPSP), formed as a component of the HM-ITSC, provides a mechanism to achieve this goal.

As originally conceived and mandated by the NCI, HM-TPSP projects are those with pre-existing data to support the clinical relevance of this work, but that require additional data to validate existing findings, define the prevalence in a larger study cohort to establish statistical significance, define risk class or generate similar data to facilitate rapid incorporation of data in the next clinical trial. Although discovery phase efforts are an important part of COG translational efforts, per NCI mandate, the HM-ITSC mechanism is to support projects with pre-existing data from primary patient samples. Proposals focused primarily on new discovery or those supported only by cell line data will not be considered.