This FOA is the Department of Energy DOE's annual, broad, open solicitation that covers all research areas in the Office of Science SC and is open throughout the Fiscal Year. Any research within SC’s Congressionally-authorized mission may be proposed under this FOA. This FOA will remain open until September 30, 2022, 11:59 PM Eastern Time, or until it is succeeded by another issuance, whichever occurs first. This FOA succeeds DE-FOA-0002414, which was published October 1, 2020.

PDF to  DE-FOA-0002562   https://science.osti.gov/-/media/grants/pdf/foas/2022/SC_FOA_0002562.pdf
The Pre-Application is optional/encouraged.
DOE Office of Science funding opps   https://science.osti.gov/Funding-Opportunities

The Office of Science of the Department of Energy hereby announces its continuing interest in receiving grant applications for support of work in the following program areas:
Advanced Scientific Computing Research,
Basic Energy Sciences,
Biological and Environmental Research,
Fusion Energy Sciences,
High Energy Physics,
Nuclear Physics,
Isotope R&D and Production, and
Accelerator R&D and Production.