Alliance for Cancer Gene Therapy, Inc. (ACGT) funds research aimed at furthering the development of cell and gene therapy approaches to the treatment of cancer.
 

2019 Investigator’s Award in Cell and Gene Therapy for Cancer
RESEARCH GRANT       
Abstract Deadline March 12, 2019 at 11 am EST
Invitation to Submit application: April 9, 2019 and deadline for invited applications: May 20, 2019 at 11 am EST.

RESEARCH OBJECTIVES

This award is for those conducting cell and gene therapy research in the following areas:

• Technology for systemic delivery and treatment of metastatic disease that could involve novel tumor-targeted delivery vehicles (e.g. tumor-homing cells, nanoparticles and new recombinant viruses).
• Altering the tumor cell microenvironment to support the induction of anti-tumor immunity
• Identification of novel tumor targets
• Novel approaches to either protective adoptively transferred cells from metabolic changes or alter the metabolism of transferred cells.

Preference will be given to those working in solid tumors, orphan tumors or pediatric tumors, and to research not previously funded, thus highly innovative proposals.

ELIGIBILITY REQUIREMENTS
Candidates for the 2019 Investigator’s Award in Cell and Gene Therapy for Cancer must hold an MD, PhD, or equivalent degree and must be tenure-track or tenured faculty. The investigator must be conducting original research as an independent faculty member. ACGT has no citizenship restrictions, and research supported by the award must be conducted at academic medical centers or research centers located in the United States or Canada.

FINANCIAL INFORMATION 
The award provides up to a maximum of $500,000 distributed over 2-3 years, inclusive of a maximum of 10% indirect costs. The funds may be used at the recipient’s discretion for salary, technical assistance, supplies, animals or capital equipment, but may not support staff not directly related to the project, e.g. secretaries or administrative assistants.  Purchase of equipment is not allowed in the final year of the grant.  Continued support is contingent upon submission and approval of a non-competitive renewal application each year. 

APPLICATION PROCEDURES
There is a two-step process for submitting applications electronically via proposalCENTRAL. Access is available using links provided in the ACGT website, www.acgtfoundation.org or directly through the proposalCENTRAL website at:  https://proposalcentral.altum.com/Login.asp. 

 A candidate must submit the following by the required deadlines:

• Step 1:  A pre-application (called Letter of Intent [LOI] on proposalCENTRAL site) that includes an abstract of the proposed research and an updated biographical sketch. The LOI/abstracts will then be reviewed by the Scientific Advisory  Council and those selected will be invited to submit full applications

• Step II:  For those invited to submit, a completed electronic application, including templates and a Signed Administrative and Signature Page(s) scanned and attached to the front of the completed application template