Sponsor link https://prodnmss.blob.core.windows.net/cmssite/nationalmssociety/media/m...

Areas of specific interest may include but are not limited to:

• Mechanistic study of remyelination and/or neural repair associated with rehabilitation and other non-pharmacological approaches to restore function

• Collaborative approaches that combine mechanistic studies with rehabilitation methods and other non-pharmacological strategies

• Clinical studies can be complemented by pre-clinical animal work

• Interaction among and between demographic features (e.g., age, race, ethnicity) and common MS symptoms such as fatigue, depression, pain, cognition, and walking

• Identification of timing, dosing, setting, and specificity of exercise to restore function

• Evaluation of outcomes (e.g., behavioral, physiologic, imaging) that show evidence to detect a meaningful change in function

• Synergistic studies of pharmacologic and non-pharmacologic therapies

• Use of technology for enhancing treatment effectiveness and for understanding the mechanisms of treatment effects

• Identification of biomarkers and tools that establish direct relationships between physiologic findings and meaningful recovery of function