Engineering Biology and Health cluster: 1) Biophotonics program; 2) Biosensing program; 3) the Cellular and Biochemical Engineering program; 4) the Disability and Rehabilitation Engineering program; and 5) the Engineering of Biomedical Systems program.
Biophotonics Program PD 21-7236 https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=505719 accepted anytime. Research topics in this program include:
- Imaging in the second near infrared window: Research that advances medical applications of biophotonics in the second near-infrared window (NIR-II: 1,000-1,700 nm) in which biological tissues are transparent up to several centimeters in depth, making this spectral window ideal for deep tissue imaging.
- Macromolecule markers: Innovative methods for labeling of macromolecules. Novel compositions of matter. Methods of fabrication of multicolor probes that could be used for marking and detection of specific pathological cells. Pushing the envelope of optical sensing to the limits of detection, resolution, and identification.
- Low coherence sensing at the nanoscale: Low coherence enhanced backscattering (LEBS). N-dimensional elastic light scattering. Angle-resolved low coherence interferometry for early cancer detection (dysplasia).
- Neurophotonics: Studies of photon activation of neurons at the interface of nanomaterials attached to cells. Development and application of biocompatible photonic tools such as parallel interfaces and interconnects for communicating and control of neural networks.
- Microphotonics and nanophotonics: Development and application of novel nanoparticle fluorescent quantum-dots. Sensitive, multiplexed, high-throughput characterization of macromolecular properties of cells. Nanomaterials and nanodevices for biomedicine.
- Optogenetics: Novel research in employing light-activated channels and enzymes for manipulation of neural activity with temporal precision. Utilizing nanophotonics, nanofibers, and genetic techniques for mapping and studying in real-time physiological processes in organs such as the brain and heart.